Products/Lung Cancer Cell Models

Boulder Lung Cell Model

Boulder Lung Cell Model


 

Product Family: Boulder Lung Cell Model
Disease Area: Cancer
Tissue Type: Lung
Clinical Diagnosis: Squamous cell carcinoma


Disease Area: Cancer
Tissue Type: Lung
Clinical Diagnosis: Squamous cell carcinoma
Age: 65-70
Sex: Male
Ethnicity: Caucasian
TNM Stage: T1aN0MX
Grade: IA
Treatment History: No prior treatment
Co-indications: Abdominal aneurysm, Chronic obstructive pulmonary disease, Gastroesophageal reflux disease, Hiatal hernia, Hypertension, Hyperlipidemia, Motion sickness, Shortness of breath, Transient ischemic attack, Inguinal hernia with surgical repair, Appendectomy, Tonsillectomy, Cataracts with surgical intervention, Surgery of the mandible, Emphysema
Medications: Prednisone, Budesonide and formoterol fumarate, Pantoprazole, Tiotropium, Amlodipine, Chondroitin and glucosamine and methylsulfonylmethane, Albuterol, Pravastatin
Country of Collection: United States
Year of Origin: 2016


MORPHOLOGY (2D)

 

MUTATIONS

 

Gene

Alteration

Frequency (%)

Exon

Result

APC

K2524E

63

16

Mutated, Variant of Unknown Significance

SMARCA4

T1425S

62

31

Mutated, Variant of Unknown Significance

ATM

T1697A

54

34

Mutated, Variant of Unknown Significance

TP53

R248L

37

7

Mutated, Pathogenic

PTPN11

R498L

35

13

Mutated, Pathogenic

CDKN2A

R58Q

33

2

Mutated, Variant of Unknown Significance

CDKN2A

L16fs

29

1

Mutated, Pathogenic

SMO

L23dup

16

1

Mutated, Presumed Benign

TSC1

R204H

9

7

Mutated, Variant of Unknown Significance

 

BOULDER DRUG RESPONSE

 

The Boulder Cell Model demonstrates sensitivity to Cisplatin and Etoposide, while showing resistance to Larotrectinib.

BOULDER GROWTH CHARACTERISTICS

The growth curve of Boulder demonstrates consistent and rapid growth. Boulder cells grow continuously for 15+ passages.

 


 

CELL LINE PROTOCOL

See Passaging Protocol: Lung Cohort for detailed Protocol

STORAGE AND SAFETY

Storage and Stability: Store frozen in liquid nitrogen.

Quality Control: All lots are tested for consistent growth capabilities. See Certificate of Analysis for further details.

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Regular price
$985.00
Sale price
$985.00
Regular price
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Unit price
per 

SIZE
1 Million Cells per Cryovial

AVAILABILITY
In stock

PRODUCT CODE
CB-0303