Products/Cancer Cell Models

Boulder Lung Cell Model

Product Family: Boulder Lung Cell Model
Disease Area: Cancer
Tissue Type: Lung
Clinical Diagnosis: Squamous cell carcinoma

Disease Area:	Cancer
Tissue Type:	Lung
Clinical Diagnosis:	Squamous cell carcinoma
Age:	65-70
Sex:	Male
Ethnicity:	Caucasian
TNM Stage:	T1aN0MX
Grade:	IA
Treatment History:	No prior treatment
Co-indications:	Abdominal aneurysm, Chronic obstructive pulmonary disease, Gastroesophageal reflux disease, Hiatal hernia, Hypertension, Hyperlipidemia, Motion sickness, Shortness of breath, Transient ischemic attack, Inguinal hernia with surgical repair, Appendectomy, Tonsillectomy, Cataracts with surgical intervention, Surgery of the mandible, Emphysema
Medications:	Prednisone, Budesonide and formoterol fumarate, Pantoprazole, Tiotropium, Amlodipine, Chondroitin and glucosamine and methylsulfonylmethane, Albuterol, Pravastatin
Country of Collection:	United States
Year of Origin:	2016

MORPHOLOGY (2D)

MUTATIONS

Gene	Alteration	Frequency (%)	Exon	Result
APC	K2524E	63	16	Mutated, Variant of Unknown Significance
SMARCA4	T1425S	62	31	Mutated, Variant of Unknown Significance
ATM	T1697A	54	34	Mutated, Variant of Unknown Significance
TP53	R248L	37	7	Mutated, Pathogenic
PTPN11	R498L	35	13	Mutated, Pathogenic
CDKN2A	R58Q	33	2	Mutated, Variant of Unknown Significance
CDKN2A	L16fs	29	1	Mutated, Pathogenic
SMO	L23dup	16	1	Mutated, Presumed Benign
TSC1	R204H	9	7	Mutated, Variant of Unknown Significance