Products/Cancer Cell Models
Powder Ovarian Cell Model
The Powder cell model originates from serous carcinoma of the ovary.
General Information
The Powder cell model originates from serous carcinoma of the ovary.
Product Family: Powder Ovarian Cell Model
Disease Area: Cancer
Tissue Type: Ovary
Clinical Diagnosis: Serous carcinoma of the ovary
Clinical Profile
| Disease Area: | Cancer |
| Tissue Type: | Ovary |
| Clinical Diagnosis: | Serous carcinoma of the ovary |
| Age: | 65-69 |
| Sex: | Female |
| Ethnicity: | Caucasian |
| TNM Stage: | T3cN1M1 |
| Grade: | IV |
| Co-indications: | N/A |
| Medications: | Adderall, Fosamax, Claritin, Calcium Carbonate and Vitamin D, Effexor, Hydrocodone and Acetaminophen, Triamterene |
| Country of Collection: | United States |
| Year of Origin: | 2012 |
Characteristics
Gene Mutations
| Gene | Alteration | Frequency (%) | Exon | Result |
| SMO | L23dup | 28 | 1 | Mutated, Presumed Benign |
Powder Growth Characteristics
The historical growth curve of Powder demonstrates consistent growth and highlights the lack of cell crisis.
STR Profile
AMEL: X
CSF1PO: 11, 12
D13S317: 12
D16S539: 9, 11
D18S51: 14, 19
D21S11: 28, 31.2
D3S1358: 14, 16
D5S818: 12
D7S820: 9
D8S1179: 11, 13
FGA: 22, 23
Penta D: 12, 13
Penta E: 13, 17
TH01: 7, 8
TPOX: 8, 9
vWA: 17, 19
Immunohistochemistry
Tumor sample diagnosis was confirmed by histology and immunohistochemical detection of tumor markers.
Lineage Markers
Immunofluorescence detection of lineage markers confirm epithelial phenotype using CK7 with DAPI overlay.
Tumorsphere Formation
Spontaneous formation of tumorspheres under low-attachment conditions.
N/A
Documentation
Storage and Stability: Store frozen in liquid nitrogen.
Care and Use Instructions: See protocol for further details
Quality Control: All lots are tested for microbial and viral contamination, cell line cross-contamination, mycoplasma, and consistent growth capabilities. See Certificate of Analysis for further details.