Products/Cancer Cell Models

Throne Lung Cell Model

Throne Lung Cell Model


 

Product Family: Throne Lung Cell Model
Disease Area: Cancer
Tissue Type: Lung
Clinical Diagnosis: Adenocarcinoma, Mixed Subtype


Disease Area: Cancer
Tissue Type: Lung
Clinical Diagnosis: Adenocarcinoma, Mixed Subtype
Age: 80-85
Sex: Male
Ethnicity: Unknown
TNM Stage: T2aN2MX
Grade: IIIA
Treatment History: No prior treatment
Co-indications: Right lung, non-small cell carcinoma, Melanoma of the nose, Knee replacement surgery, Tonsillectomy, Arthritis, Hypertension, Hypercholesterolemia
Medications: Simvastatin, Omeprazole, Montelukast, Lisinopril, Hydrochlorothiazide, Acetaminophen and hydrocodone, Fluticasone nasal, Celecoxib, Finasteride, Doxazosin, Benzonatate, Ascorbic acid
Country of Collection: United States
Year of Origin: 2016


MORPHOLOGY (2D)

 

MUTATIONS

 

Gene

Alteration

Frequency (%)

Exon

Result

POT1

G95C

29

8

Mutated, Variant of Unknown Significance

BRAF

G464V

26

11

Mutated, Pathogenic

KRAS

G13C

26

2

Mutated, Pathogenic

NF1

P678fs

17

18

Mutated, Pathogenic

POT1

E262X

15

10

Mutated, Pathogenic

 

THRONE DRUG RESPONSE

 

The Throne Cell Model demonstrates sensitivity to Cisplatin and Etoposide, while showing resistance to Larotrectinib.

THRONE GROWTH CHARACTERISTICS

The growth curve of Throne demonstrates consistent and rapid growth. Throne cells grow continuously for 15+ passages.

 


CELL LINE PROTOCOL

See Passaging Protocol: Lung Cohort for detailed Protocol

STORAGE AND SAFETY

Storage and Stability: Store frozen in liquid nitrogen.

Quality Control: All lots are tested for consistent growth capabilities. See Certificate of Analysis for further details.

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Regular price
$985.00
Sale price
$985.00
Regular price
Sold out
Unit price
per 

SIZE
1 Million Cells per Cryovial

AVAILABILITY
In stock

PRODUCT CODE
CB-0305